diff --git a/Cargo.lock b/Cargo.lock
index a811222..9568e2b 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -44,18 +44,6 @@ dependencies = [
  "winapi",
 ]
 
-[[package]]
-name = "arrayref"
-version = "0.3.6"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "a4c527152e37cf757a3f78aae5a06fbeefdb07ccc535c980a3208ee3060dd544"
-
-[[package]]
-name = "arrayvec"
-version = "0.5.1"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "cff77d8686867eceff3105329d4698d96c2391c176d5d03adc90c7389162b5b8"
-
 [[package]]
 name = "atty"
 version = "0.2.14"
@@ -87,12 +75,6 @@ dependencies = [
  "rustc-demangle",
 ]
 
-[[package]]
-name = "base64"
-version = "0.11.0"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "b41b7ea54a0c9d92199de89e20e58d49f02f8e699814ef3fdf266f6f748d15c7"
-
 [[package]]
 name = "bindgen"
 version = "0.36.1"
@@ -125,17 +107,6 @@ version = "1.2.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "cf1de2fe8c75bc145a2f577add951f8134889b4795d47466a54a5c846d691693"
 
-[[package]]
-name = "blake2b_simd"
-version = "0.5.10"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "d8fb2d74254a3a0b5cac33ac9f8ed0e44aa50378d9dbb2e5d83bd21ed1dc2c8a"
-dependencies = [
- "arrayref",
- "arrayvec",
- "constant_time_eq",
-]
-
 [[package]]
 name = "bstr"
 version = "0.2.13"
@@ -175,17 +146,6 @@ version = "0.1.10"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "4785bdd1c96b2a846b2bd7cc02e86b6b3dbf14e7e53446c4f54c92a361040822"
 
-[[package]]
-name = "chrono"
-version = "0.4.11"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "80094f509cf8b5ae86a4966a39b3ff66cd7e2a3e594accec3743ff3fabeab5b2"
-dependencies = [
- "num-integer",
- "num-traits",
- "time",
-]
-
 [[package]]
 name = "clang-sys"
 version = "0.22.0"
@@ -212,12 +172,6 @@ dependencies = [
  "vec_map",
 ]
 
-[[package]]
-name = "constant_time_eq"
-version = "0.1.5"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "245097e9a4535ee1e3e3931fcfcd55a796a44c643e8596ff6566d68f09b87bbc"
-
 [[package]]
 name = "crossbeam-deque"
 version = "0.7.3"
@@ -274,7 +228,7 @@ checksum = "00affe7f6ab566df61b4be3ce8cf16bc2576bca0963ceb0955e45d514bf9a279"
 dependencies = [
  "bstr",
  "csv-core",
- "itoa",
+ "itoa 0.4.6",
  "ryu",
  "serde",
 ]
@@ -301,15 +255,10 @@ source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "72aa14c04dfae8dd7d8a2b1cb7ca2152618cd01336dbfe704b8dcbf8d41dbd69"
 
 [[package]]
-name = "dirs"
-version = "1.0.5"
+name = "deranged"
+version = "0.3.7"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "3fd78930633bd1c6e35c4b42b1df7b0cbc6bc191146e512bb3bedf243fcc3901"
-dependencies = [
- "libc",
- "redox_users",
- "winapi",
-]
+checksum = "7684a49fb1af197853ef7b2ee694bc1f5b4179556f1e5710e1760c5db6f5e929"
 
 [[package]]
 name = "either"
@@ -460,6 +409,12 @@ version = "0.4.6"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "dc6f3ad7b9d11a0c00842ff8de1b60ee58661048eb8049ed33c73594f359d7e6"
 
+[[package]]
+name = "itoa"
+version = "1.0.9"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "af150ab688ff2122fcef229be89cb50dd66af9e01a4ff320cc137eecc9bacc38"
+
 [[package]]
 name = "lazy_static"
 version = "0.2.11"
@@ -474,9 +429,9 @@ checksum = "e2abad23fbc42b3700f2f279844dc832adb2b2eb069b2df918f455c4e18cc646"
 
 [[package]]
 name = "libc"
-version = "0.2.71"
+version = "0.2.147"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "9457b06509d27052635f90d6466700c65095fdf75409b3fbdd903e988b886f49"
+checksum = "b4668fb0ea861c1df094127ac5f1da3409a82116a4ba74fca2e58ef927159bb3"
 
 [[package]]
 name = "libloading"
@@ -564,31 +519,21 @@ dependencies = [
 ]
 
 [[package]]
-name = "num-integer"
-version = "0.1.43"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "8d59457e662d541ba17869cf51cf177c0b5f0cbf476c66bdc90bf1edac4f875b"
-dependencies = [
- "autocfg",
- "num-traits",
-]
-
-[[package]]
-name = "num-traits"
-version = "0.2.12"
+name = "num_cpus"
+version = "1.13.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "ac267bcc07f48ee5f8935ab0d24f316fb722d7a1292e2913f0cc196b29ffd611"
+checksum = "05499f3756671c15885fee9034446956fff3f243d6077b91e5767df161f766b3"
 dependencies = [
- "autocfg",
+ "hermit-abi",
+ "libc",
 ]
 
 [[package]]
-name = "num_cpus"
-version = "1.13.0"
+name = "num_threads"
+version = "0.1.6"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "05499f3756671c15885fee9034446956fff3f243d6077b91e5767df161f766b3"
+checksum = "2819ce041d2ee131036f4fc9d6ae7ae125a3a40e97ba64d04fe799ad9dabbb44"
 dependencies = [
- "hermit-abi",
  "libc",
 ]
 
@@ -739,17 +684,6 @@ version = "0.1.56"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "2439c63f3f6139d1b57529d16bc3b8bb855230c8efcc5d3a896c8bea7c3b1e84"
 
-[[package]]
-name = "redox_users"
-version = "0.3.4"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "09b23093265f8d200fa7b4c2c76297f47e681c655f6f1285a8780d6a022f7431"
-dependencies = [
- "getrandom",
- "redox_syscall",
- "rust-argon2",
-]
-
 [[package]]
 name = "regex"
 version = "0.2.11"
@@ -822,18 +756,6 @@ dependencies = [
  "winapi",
 ]
 
-[[package]]
-name = "rust-argon2"
-version = "0.7.0"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "2bc8af4bda8e1ff4932523b94d3dd20ee30a87232323eda55903ffd71d2fb017"
-dependencies = [
- "base64",
- "blake2b_simd",
- "constant_time_eq",
- "crossbeam-utils",
-]
-
 [[package]]
 name = "rust-htslib"
 version = "0.20.0"
@@ -890,9 +812,9 @@ checksum = "d4f410fedcf71af0345d7607d246e7ad15faaadd49d240ee3b24e5dc21a820ac"
 
 [[package]]
 name = "serde"
-version = "1.0.113"
+version = "1.0.183"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "6135c78461981c79497158ef777264c51d9d0f4f3fc3a4d22b915900e42dac6a"
+checksum = "32ac8da02677876d532745a130fc9d8e6edfa81a269b107c5b00829b91d8eb3c"
 
 [[package]]
 name = "serde_derive"
@@ -907,13 +829,13 @@ dependencies = [
 
 [[package]]
 name = "simplelog"
-version = "0.5.3"
+version = "0.12.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "2e95345f185d5adeb8ec93459d2dc99654e294cc6ccf5b75414d8ea262de9a13"
+checksum = "acee08041c5de3d5048c8b3f6f13fafb3026b24ba43c6a695a0c76179b844369"
 dependencies = [
- "chrono",
  "log",
- "term",
+ "termcolor",
+ "time",
 ]
 
 [[package]]
@@ -984,17 +906,6 @@ dependencies = [
  "winapi",
 ]
 
-[[package]]
-name = "term"
-version = "0.5.2"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "edd106a334b7657c10b7c540a0106114feadeb4dc314513e97df481d5d966f42"
-dependencies = [
- "byteorder",
- "dirs",
- "winapi",
-]
-
 [[package]]
 name = "termcolor"
 version = "1.1.0"
@@ -1043,12 +954,32 @@ dependencies = [
 
 [[package]]
 name = "time"
-version = "0.1.43"
+version = "0.3.25"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "ca8a50ef2360fbd1eeb0ecd46795a87a19024eb4b53c5dc916ca1fd95fe62438"
+checksum = "b0fdd63d58b18d663fbdf70e049f00a22c8e42be082203be7f26589213cd75ea"
 dependencies = [
+ "deranged",
+ "itoa 1.0.9",
  "libc",
- "winapi",
+ "num_threads",
+ "serde",
+ "time-core",
+ "time-macros",
+]
+
+[[package]]
+name = "time-core"
+version = "0.1.1"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "7300fbefb4dadc1af235a9cef3737cea692a9d97e1b9cbcd4ebdae6f8868e6fb"
+
+[[package]]
+name = "time-macros"
+version = "0.2.11"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "eb71511c991639bb078fd5bf97757e03914361c48100d52878b8e52b46fb92cd"
+dependencies = [
+ "time-core",
 ]
 
 [[package]]
diff --git a/Cargo.toml b/Cargo.toml
index ca327aa..cfad836 100644
--- a/Cargo.toml
+++ b/Cargo.toml
@@ -10,7 +10,7 @@ failure = "*"
 clap = "*"
 terminal_size = "*"
 human-panic = "1.0.1"
-simplelog = "0.5.0"
+simplelog = "0.12.1"
 log = "*"
 tempfile = "*"
 rayon = "*"