diff --git a/skills/boxuan-zhao/rdkit-nature-style/SKILL.md b/skills/boxuan-zhao/rdkit-nature-style/SKILL.md
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+---
+name: rdkit-nature-style
+description: "Render molecules with RDKit in a measured, monochrome Nature-like publication style using fixed physical bond length, line width, Arial typography, balanced atom-label clearance, SVG or PNG output, and mandatory post-render measurements. Use when a user asks for Nature-style, journal-style, publication-ready, or physically calibrated RDKit structure drawings without molecular-region emphasis."
+---
+
+# RDKit Nature Style
+
+Treat "Nature style" as a local Nature-like preset, not an official RDKit or Nature preset. Preserve chemical structure and stereochemistry; change presentation only.
+
+## Workflow
+
+1. Confirm RDKit is available.
+2. Run `scripts/render_nature_style.py` with a SMILES and output path.
+3. Prefer SVG for publication and editability. Use PNG only when raster output is requested.
+4. Read the generated `*.measurements.json` after every render.
+5. Reject the result if the command reports a bond-length tolerance failure.
+6. Visually inspect the finished structure for label collisions, excessive label clearance, clipping, and stereo legibility.
+
+```bash
+python scripts/render_nature_style.py \
+  --smiles 'ClC1=CC(C=O)=C(O)C2=C1OCC2' \
+  --output molecule.svg
+```
+
+## Preset
+
+- Mean atom-center bond length: 0.381 cm.
+- Bond line width: 0.021 cm.
+- Multiple-bond offset: 18% of bond length.
+- Font: Arial Regular when `arial.ttf` is found; otherwise RDKit's built-in font.
+- Font size: 6 pt.
+- Extra atom-label padding: 0.035 in RDKit relative units.
+- Foreground/background: black on white.
+- Atom indices: hidden.
+
+Do not pass physical centimetres directly to `MolDrawOptions`. The script converts cm and pt at render time using `--dpi`, normalizes `fixedBondLength` by `MeanBondLength(mol)`, and then measures the final atom coordinates. RDKit's `fixedBondLength` is pixels per molecule-coordinate unit, not the final atom-to-atom length.
+
+## Controls
+
+```bash
+python scripts/render_nature_style.py --help
+```
+
+Use the default 520 by 380 canvas for ordinary small molecules. Increase the canvas for larger molecules. Do not use `--width -1 --height -1` when physical bond length must be preserved: RDKit flexiCanvas rescales the drawing. A canvas may add whitespace or constrain the structure, but it must not define the intended bond, stroke, or font dimensions; the post-render measurement is authoritative.
+
+Only change `--label-padding` to tune bond-to-label clearance. Do not compensate by changing bond length or font size. Use small increments such as 0.005.
+
+## Validation
+
+Require all of the following:
+
+- The molecule parses and sanitizes.
+- Every final atom-center bond length is measured.
+- The mean bond length is within `--tolerance-cm` of the requested value.
+- For SVG, actual emitted `stroke-width` values are extracted and converted back to cm.
+- The configured font size is converted back to pt.
+- The measurement JSON accompanies the output.
+- The molecule is re-parsed from the input; drawing must not change its chemistry.
+
+State measured values rather than claiming exact journal compliance. Nature journals may impose figure-level requirements outside a molecular renderer, including final panel dimensions, reduction, file format, and editorial typography.
diff --git a/skills/boxuan-zhao/rdkit-nature-style/agents/openai.yaml b/skills/boxuan-zhao/rdkit-nature-style/agents/openai.yaml
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+interface:
+  display_name: "RDKit Nature Style"
+  short_description: "Render measured publication-style molecular figures with RDKit"
+  default_prompt: "Use $rdkit-nature-style to render this molecule in a measured Nature-like publication style."
diff --git a/skills/boxuan-zhao/rdkit-nature-style/scripts/render_nature_style.py b/skills/boxuan-zhao/rdkit-nature-style/scripts/render_nature_style.py
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+++ b/skills/boxuan-zhao/rdkit-nature-style/scripts/render_nature_style.py
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+#!/usr/bin/env python3
+"""Render and measure a monochrome Nature-like RDKit structure drawing."""
+
+from __future__ import annotations
+
+import argparse
+import json
+import math
+import re
+from pathlib import Path
+
+from rdkit import Chem
+from rdkit.Chem import AllChem
+from rdkit.Chem.Draw import rdMolDraw2D
+
+
+CM_PER_INCH = 2.54
+
+
+def cm_to_px(value_cm: float, dpi: float) -> float:
+    return value_cm * dpi / CM_PER_INCH
+
+
+def pt_to_px(value_pt: float, dpi: float) -> float:
+    return value_pt * dpi / 72.0
+
+
+def apply_style(drawer, mol, args) -> None:
+    opts = drawer.drawOptions()
+    coordinate_bond_length = rdMolDraw2D.MeanBondLength(mol)
+    if coordinate_bond_length <= 0:
+        raise ValueError("Cannot determine a positive mean coordinate bond length")
+
+    opts.fixedBondLength = cm_to_px(args.bond_length_cm, args.dpi) / coordinate_bond_length
+    opts.bondLineWidth = cm_to_px(args.line_width_cm, args.dpi)
+    opts.scaleBondWidth = False
+    opts.multipleBondOffset = args.multiple_bond_offset
+    opts.fixedFontSize = round(pt_to_px(args.font_size_pt, args.dpi))
+    opts.minFontSize = opts.fixedFontSize
+    opts.maxFontSize = opts.fixedFontSize
+    opts.additionalAtomLabelPadding = args.label_padding
+    opts.padding = args.canvas_padding
+    opts.addAtomIndices = False
+    opts.explicitMethyl = False
+    opts.prepareMolsBeforeDrawing = True
+    opts.clearBackground = True
+
+    font = Path(args.font_file) if args.font_file else Path(r"C:\Windows\Fonts\arial.ttf")
+    if font.is_file():
+        opts.fontFile = str(font)
+    rdMolDraw2D.SetMonochromeMode(opts, (0, 0, 0), (1, 1, 1))
+
+
+def measure(drawer, mol, args, svg: str | None) -> dict:
+    lengths_px = []
+    for bond in mol.GetBonds():
+        start = drawer.GetDrawCoords(bond.GetBeginAtomIdx())
+        end = drawer.GetDrawCoords(bond.GetEndAtomIdx())
+        lengths_px.append(math.hypot(end.x - start.x, end.y - start.y))
+    if not lengths_px:
+        raise ValueError("Measurement requires at least one bond")
+
+    strokes_px = [] if svg is None else [
+        float(value) for value in re.findall(r"stroke-width:([0-9.]+)px", svg)
+    ]
+    opts = drawer.drawOptions()
+    mean_px = sum(lengths_px) / len(lengths_px)
+    return {
+        "dpi": args.dpi,
+        "bond_count": len(lengths_px),
+        "bond_lengths_px": [round(value, 4) for value in lengths_px],
+        "bond_lengths_cm": [round(value * CM_PER_INCH / args.dpi, 6) for value in lengths_px],
+        "mean_bond_length_px": round(mean_px, 4),
+        "mean_bond_length_cm": round(mean_px * CM_PER_INCH / args.dpi, 6),
+        "svg_stroke_widths_px": sorted(set(strokes_px)),
+        "svg_stroke_widths_cm": sorted({round(value * CM_PER_INCH / args.dpi, 6) for value in strokes_px}),
+        "font_size_px": opts.fixedFontSize,
+        "font_size_pt": round(opts.fixedFontSize * 72 / args.dpi, 4),
+        "label_padding": opts.additionalAtomLabelPadding,
+    }
+
+
+def render(args) -> dict:
+    mol = Chem.MolFromSmiles(args.smiles)
+    if mol is None:
+        raise ValueError(f"Invalid SMILES: {args.smiles}")
+    canonical_before = Chem.MolToSmiles(mol, isomericSmiles=True)
+    AllChem.Compute2DCoords(mol)
+
+    suffix = args.output.suffix.lower()
+    if suffix == ".svg":
+        drawer = rdMolDraw2D.MolDraw2DSVG(args.width, args.height)
+    elif suffix == ".png":
+        if args.width < 1 or args.height < 1:
+            raise ValueError("PNG output requires positive --width and --height")
+        drawer = rdMolDraw2D.MolDraw2DCairo(args.width, args.height)
+    else:
+        raise ValueError("Output extension must be .svg or .png")
+
+    apply_style(drawer, mol, args)
+    drawer.DrawMolecule(mol)
+    drawer.FinishDrawing()
+    data = drawer.GetDrawingText()
+    report = measure(drawer, mol, args, data if suffix == ".svg" else None)
+    report["canonical_smiles"] = canonical_before
+
+    args.output.parent.mkdir(parents=True, exist_ok=True)
+    if suffix == ".svg":
+        args.output.write_text(data, encoding="utf-8")
+    else:
+        args.output.write_bytes(data)
+    args.output.with_suffix(args.output.suffix + ".measurements.json").write_text(
+        json.dumps(report, indent=2), encoding="utf-8"
+    )
+    return report
+
+
+def parser() -> argparse.ArgumentParser:
+    result = argparse.ArgumentParser(description=__doc__)
+    result.add_argument("--smiles", required=True)
+    result.add_argument("--output", required=True, type=Path)
+    result.add_argument("--width", type=int, default=520)
+    result.add_argument("--height", type=int, default=380)
+    result.add_argument("--dpi", type=float, default=300.0)
+    result.add_argument("--bond-length-cm", type=float, default=0.381)
+    result.add_argument("--line-width-cm", type=float, default=0.021)
+    result.add_argument("--font-size-pt", type=float, default=6.0)
+    result.add_argument("--multiple-bond-offset", type=float, default=0.18)
+    result.add_argument("--label-padding", type=float, default=0.035)
+    result.add_argument("--canvas-padding", type=float, default=0.06)
+    result.add_argument("--font-file")
+    result.add_argument("--tolerance-cm", type=float, default=0.005)
+    return result
+
+
+def main() -> None:
+    args = parser().parse_args()
+    report = render(args)
+    print(json.dumps(report, indent=2))
+    error = abs(report["mean_bond_length_cm"] - args.bond_length_cm)
+    if error > args.tolerance_cm:
+        raise SystemExit(
+            f"MEASUREMENT FAILED: mean bond length error {error:.6f} cm exceeds "
+            f"tolerance {args.tolerance_cm:.6f} cm"
+        )
+
+
+if __name__ == "__main__":
+    main()