diff --git a/.github/workflows/test-python.yml b/.github/workflows/test-python.yml
index b1f2f71..083ab1a 100644
--- a/.github/workflows/test-python.yml
+++ b/.github/workflows/test-python.yml
@@ -12,13 +12,13 @@ on:
 
 jobs:
   run_unix_tests:
+    env:
+      UV_SYSTEM_PYTHON: 1
+
     name: Run Python tests on Ubuntu
     runs-on: ubuntu-latest
     steps:
       - uses: actions/checkout@v4
-      - uses: actions/setup-python@v5
-        with:
-          python-version: '3.9'
 
       - name: Install Clang
         run: |
@@ -41,12 +41,20 @@ jobs:
           ./get_sources
         working-directory: ./package
 
+      - name: Install uv
+        uses: astral-sh/setup-uv@v7
+        with:
+          python-version: '3.9'
+
+      - name: Set up Python
+        run: uv python install
+
       - name: Install NucleoFind
-        run: pip install .
+        run: uv pip install . --break-system-packages
         working-directory: ./package
 
       - name: Install pytest
-        run: pip install pytest
+        run: uv pip install pytest --break-system-packages
 
       - name: Install NucleoFind models
         run: |
@@ -54,17 +62,17 @@ jobs:
           nucleofind-install -m nano
 
       - name: Run tests
-        run : pytest tests
+        run: uv run pytest tests
         working-directory: ./package
 
   run_windows_tests:
     name: Run Python tests on Windows
     runs-on: windows-latest
+    env:
+      UV_SYSTEM_PYTHON: 1
+
     steps:
       - uses: actions/checkout@v4
-      - uses: actions/setup-python@v4
-        with:
-          python-version: '3.9'
 
       - uses: TheMrMilchmann/setup-msvc-dev@v3
         with:
@@ -76,31 +84,39 @@ jobs:
           sh get_sources
         working-directory: ./package
 
+      - name: Install uv
+        uses: astral-sh/setup-uv@v7
+        with:
+          python-version: '3.9'
+
+      - name: Set up Python
+        run: uv python install
+
       - name: Install NucleoFind
-        run: pip install .
+        run: uv pip install . --break-system-packages
         working-directory: ./package
 
       - name: Install pytest
-        run: pip install pytest
+        run: uv pip install pytest
 
       - name: Install NucleoFind models
-        run:  |
+        run: |
           nucleofind-install -m nano
           nucleofind-install -m core
 
       - name: Run tests
-        run : pytest tests
+        run: uv run pytest tests --break-system-packages
         working-directory: ./package
 
 
   debug:
-      needs: [run_unix_tests, run_windows_tests]
-      runs-on: ubuntu-latest
-      if: ${{ failure() }}
-      steps:
-        - uses: actions/checkout@v3
-        - name: Notify chat
-          uses: teknatha136/actions-google-chat-text-message@main
-          with:
-            google-chat-webhook: ${{ secrets.WEBHOOK_URL }}
-            text-message: ${{ github.actor }} attempted to merge a change into NucleoFind, but this PR failed testing. Link ${{ github.server_url }}/${{ github.repository }}/actions/runs/${{ github.run_id }} \n
\ No newline at end of file
+    needs: [ run_unix_tests, run_windows_tests ]
+    runs-on: ubuntu-latest
+    if: ${{ failure() }}
+    steps:
+      - uses: actions/checkout@v3
+      - name: Notify chat
+        uses: teknatha136/actions-google-chat-text-message@main
+        with:
+          google-chat-webhook: ${{ secrets.WEBHOOK_URL }}
+          text-message: ${{ github.actor }} attempted to merge a change into NucleoFind, but this PR failed testing. Link ${{ github.server_url }}/${{ github.repository }}/actions/runs/${{ github.run_id }} \n
\ No newline at end of file