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Introduction

This repo stores the CaseOnly R code for simulating and analysing data to evaluate type I error and power of the case-only design to detect interactions.

Citation

Please cite the following paper if you use it.

Dong R, Wang GT, DeWan AT, Leal SM. The case-only design is a powerful approach to detect interactions but should be used with caution. BMC Genomics. 2025 Mar 6;26(1):222. doi: 10.1186/s12864-025-11318-1. PMID: 40050722; PMCID: PMC11884093.