Support input of ontology/pathway terms (e.g., GO, KEGG) to visualize associated phenotype-similar gene modules

[akikuno]

📋 Description

It would be a valuable feature to allow users to input biological ontology or pathway terms—such as Gene Ontology (GO) terms or KEGG pathway identifiers—and retrieve gene modules composed of phenotype-similar genes associated with those terms.

This functionality would enable users to explore how genes involved in specific pathways or functions (e.g., "cell cycle," "insulin signaling") form phenotype-based modules, potentially revealing new insights into in vivo functional relationships.

Proposed behavior

• Users can enter GO term or KEGG pathway term.
• The system maps those terms to corresponding genes.
• Genes are filtered to identify phenotype-similar modules.
• The resulting network is visualized on the interface.

Benefit

This integration bridges well-established functional annotations with phenotypic similarity, allowing a unique and intuitive way to interpret genetic modules based on both curated knowledge and experimental phenotypes.

Idea contributed by @kinari-labwork 🎊

🔖 TSUMUGI Version

1.0.0 (preview)

📎 Anything else?

None