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Package: GeoDiff
Type: Package
Title: Count model based differential expression and normalization on GeoMx RNA data
Version: 1.1.3
Authors@R: c(person("Nicole", "Ortogero", email = "nortogero@nanostring.com", role = c("cre")),
person("Lei", "Yang", email = "lyang@nanostring.com", role = c("aut")),
person("Zhi", "Yang", email = "zyang@nanostring.com", role = c("aut")),
person("Ned", "Booker", email = "ned@procogia.com", role = c("aut")))
Description: A series of statistical models using count generating distributions
for background modelling, feature and sample QC, normalization and differential
expression analysis on GeoMx RNA data. The application of these methods are
demonstrated by example data analysis vignette.
Imports:
Matrix,
robust,
plyr,
lme4,
Rcpp (>= 1.0.4.6),
Rfast,
withr,
methods,
graphics,
stats,
testthat,
GeomxTools,
NanoStringNCTools
LinkingTo: Rcpp, RcppArmadillo, roptim
License: MIT + file LICENSE
URL: https://github.com/Nanostring-Biostats/GeoDiff
BugReports: https://github.com/Nanostring-Biostats/GeoDiff
Encoding: UTF-8
Suggests:
knitr,
rmarkdown,
dplyr
VignetteBuilder: knitr
Depends:
R (>= 4.1.0),
Biobase
RoxygenNote: 7.1.2
biocViews: GeneExpression, DifferentialExpression, Normalization