Mouse BCR

[DennisCambridge]

Hi Philip!

Thank you so much for this amazing tool! It has helped tremendously with fine T cell annotation in our mice sample. I saw that back in 2020 you added BCR, but only for human. I am wondering if we could do mouse BCR now - thank you so much in advance!

[phbradley]

Hi Dennis,
Thanks for the kind words! I'm so glad you have found conga useful. I'm afraid we still haven't added mouse bcrs, in part because I hadn't come across any test data. Do you know of any public datasets we could test things on? Or have a little one we could play with (could share this confidentially pbradley@fredhutch.org)?
Take care,
Phil

[DennisCambridge]

Hi Phil,
Thanks so much for the reply! I found two public datasets: GSE174836 and GSE174739. Would these serve the purpose?
Have a great upcoming weekend :D.
Cheers,
Dennis

[sheethal94]

Hi Philip,

I'm following up on the conversation because I'm also interested in analyzing mouse BCR data using Conga. Please let me know if you have any updates. Thanks!

[dn-ra]

Hi Philip,

Thanks for your development of Conga. I'm wondering if there is any update on making the tool work for mouse BCR data?

[phbradley]

Hi there-- I'm really sorry for the delay on this. I just added the organism "mouse_ig" to the genes database. Give it a try for mouse BCR data and let me know how it goes.