Suggestion:
A 300-ish Plasmid cost CRISPR upgrade to track which species you have MAD'd and which you have Bioseeded right on the species selection/evolution screen.
Example:
In the screen where you are about to choose your species, hovering over the species shows the level at which this species has gone through MAD and its genus went through Bioseed scenarios. With a 0-4 challenge level scale indicator. At the bottom of the species description.
Why a CRISPR upgrade?
It doesn't change the game for newcomers. Experienced players will be using some kind of achievement tracker to play completionist, and this tracker for MAD and Bioseed makes that somewhat unnecessary - at least for most playthroughs.