We need a function that allows the user to fit a simpler model for proteins that lead to a fitError.
Here is a tentative implementation for msqrobRefit():
msqrobRefit <- function(object, formula, i, subset, fcol, name,
modelColumnName, ...) {
seti <- getWithColData(object, i)
setj <- getWithColData(object, name)
if (any(!subset %in% rowData(seti)[[fcol]]))
stop("Some entries in 'subset' not found in '", fcol,
"' (rowData of set '", i, "')")
setjRefit <- msqrobAggregate(
seti[rowData(seti)[[fcol]] %in% subset, ],
formula = formula, fcol = fcol, modelColumnName = modelColumnName,
...
)
rowData(setj)[[modelColumnName]][subset] <-
rowData(setjRefit)[[modelColumnName]][subset]
modelsNew <- rowData(setj)[[modelColumnName]]
hlp <- limma::squeezeVar(
var = vapply(modelsNew, getVar, numeric(1)),
df = vapply(modelsNew, getDF, numeric(1))
)
for (ii in seq_along(modelsNew)) {
modelsNew[[ii]]@varPosterior <- as.numeric(hlp$var.post[ii])
modelsNew[[ii]]@dfPosterior <- as.numeric(hlp$df.prior + getDF(modelsNew[[ii]]))
}
rowData(object[[name]])[[modelColumnName]] <- modelsNew
object
}
We need to think carefully about this. How can a user retrieve the information about which features has been fit with which
model? We should provided a helper/getter/show function(s) that provides streamlined access to that piece of info.
We need a function that allows the user to fit a simpler model for proteins that lead to a
fitError.Here is a tentative implementation for
msqrobRefit():We need to think carefully about this. How can a user retrieve the information about which features has been fit with which
model? We should provided a helper/getter/show function(s) that provides streamlined access to that piece of info.