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A long time ago I modified phred to call hets properly in pooled samples

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DuoPhred

Date: 2006-08-01

Language: Visual C++ 2005

Early in my Ph.D. I needed to analyze some pooled Sanger reads for a somatic mutation variant calling project in the mouse mitochondrial genome. Standard phred only provided a best guess for each base, but this tool was able to recover bases that had a characteristic double peak in the chromatogram.

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A long time ago I modified phred to call hets properly in pooled samples

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