DNA Sequence Alignment App

Prerequisites

• Node.js (v16+)
• Rust (latest stable version)
• npm
• napi-rs CLI

Setup Instructions

1. Clone the repository

2. Install dependencies:

   npm install

3. Build the Rust module:

   cd native
   npm run build

4. Start the application:

   npm start

5. Open a browser and navigate to http://localhost:3000

How It Works

• Two text areas for DNA sequences
• Alignment button triggers Rust-based alignment algorithm
• Similarity score displayed as a percentage

Alignment Algorithm

Uses a Rust Needleman-Wunsch algorithm implementation.

Supports DNA bases: A, T, C, G

TODO

• Add a title and a navBar with two items, NW and Sw
• Implement SW algorithm, organize Rust code better
• Add viz for optimal path in matrix, similarly as https://bioboot.github.io/bimm143_W20/class-material/nw/
• Implement protein alignment
• Add mismatch matrix option (e.g: BLOSUM, PAM, etc...)