cth/chmm
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Constrained Hidden Markov Models in PRISM This is an implementation of a constrained hidden Markov model in PRISM. The particular implementation is a pair HMM which is usuable for constrained sequence alignment. The implementation includes a few well-known global constraints which may be used with the model. The purpose of this implementation is to illustrate implementation principles of constrained HMMs. The main file is chmm.pl which constraint the basic machinery for integration of side-constraints into PRISM models and some basic constraint checkers. Examples of PRISM models with side-constraints using this framework can be found in the examples/ directory.