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feat: split methylate from simulate; methylation truth via VCF MT/MB
- #11
#11
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tfenne
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Jun 13, 2026
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feat: split methylate from simulate; methylation truth via VCF MT/MB
#11
tfenne
merged 8 commits into
main
fg-labs/holodeck:main
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nh/bisulfite-conversion
fg-labs/holodeck:nh/bisulfite-conversion
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Commits on May 28, 2026
feat(meth): add methylation primitives and MT/MB VCF I/O
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feat(methylate): add subcommand for producing methylation-annotated VCFs
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feat(simulate): methylation chemistry driven by VCF MT/MB truth
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docs(readme): document the methylate + simulate two-command flow
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feat(simulate): model per-molecule conversion failure
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refactor(meth): address multi-agent review findings
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document golden BAM header and per-record tags (#13)
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feat(methylate): context-aware Markov methylation model (#14)
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