Storing game dip settings for individual content

[superuser-does]

More of a question in case the feature already exists.

I want to be able to store some game dip settings, for example enabling red blood in the USA version of Metal Slug. This requires a trip into Uni-BIOS on every boot.

Is there a way to store these other than relying on a save state, which interferes with game saves (and thus scoring)?

[carmiker]

Maybe NVRAM is not saving properly, will look at it.