Metabolic pathway analysis for Reactome pathways

Input: High-throughput metabolite levels for condition and control samples

Output: Ranked list of Reactome pathways that perturbed in the condition under study – the rank is based on a score or p-value that results from evaluating the pathway disruption given the data and the pathway information from the Reactome database

To build and run a docker container that has MPA follow the steps below

This runs a simple MPA analysis example.

• have the docker engine running
• have the MPA_docker folder on your computer
• build the image (run the following command in a terminal in the MPA_docker folder):

docker build --rm -t mpa_image .

• run the container:

docker run --rm mpa_image