Prime editing guide RNA prediction
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Jan 9, 2025 - Python
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prime-editing
Here are 8 public repositories matching this topic...
A variant-first, multi-modality CRISPR design framework that unifies SpCas9 nuclease, base-editor, and prime-editor chemistries under a single typed interface to deliver ranked candidate edits complete with calibrated uncertainty intervals, predicted outcome distributions, and ancestry-stratified, population-aware off-target safety reporting.
python rust machine-learning bioinformatics deep-learning genomics computational-biology crispr variant-calling clinvar uncertainty-estimation genome-editing benchmark-datasets pyo3 base-editing populationgenetics prime-editing haplotype-mapping off-target-analysis guide-rna-design
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Jul 15, 2026 - Python
A declarative DSL and compiler for reproducible gene-editing design — with LLM agents and an MCP server so any AI agent can drive it safely.
python bioinformatics compiler dsl mcp computational-biology crispr genome-editing base-editing gene-editing guide-rna prime-editing llm-agents mcp-server
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Jul 17, 2026 - Python
Repository for the code used to generate figures for Zhou et al. and running the BEAN-FUSE pipeline.
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Jun 18, 2026 - Promela
AI-assisted platform for designing CRISPR experiments — from target selection to bench-ready protocols
python bioinformatics crispr gradio base-editing gene-editing guide-rna research-tools crispri prime-editing crispor crispra
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Apr 13, 2026 - Python
Materials for the Harvard 2026 genetics bootcamp for CRISPR screening presented by Rich Sherwood's lab.
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Jan 13, 2026 - Jupyter Notebook
Python code used to scan genomic sequences and calculate Hamming distance to identify near-matching DNA regions.
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Dec 17, 2025 - Python
PROpeg — precision-optimized pegRNA design and structure visualization tool for plant prime editing (ICAR-CRRI & ICAR-IASRI)
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Jul 19, 2026 - Python
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