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wallematthias/README.md

Matthias Walle

Medical imaging · Bone microstructure · Computational mechanobiology

Lab website · Lab GitHub

I am an Assistant Professor in the Department of Radiology at the University of Calgary and a member of the McCaig Institute for Bone and Joint Health. I lead Walle Lab, where we combine medical imaging, computational modelling, and machine learning to study how mechanical forces influence tissue behaviour.

I develop research software that connects images to quantitative measurements of bone structure, mechanics, and tissue adaptation. Reproducible workflows and tools that researchers can use in practice are central to this work.

Lab software

Our lab software now lives at Walle Lab. Start with the lab GitHub homepage for the full software catalogue, installation links, and method descriptions.

Area Selected tools
User interface tools Bone Imaging Toolbox for 3D Slicer for integrated bone imaging workflows; BoneQuantMRI for quantitative bone MRI.
Microstructure tools bone-contouring, bone-microarchitecture, and bone-plate-rod-thinning for segmentation and structural analysis; TimelapsedHRpQCT and BoneMechanoregulation for longitudinal bone adaptation and its relation to mechanical stimuli.
CT tools spine-segment for vertebral CT segmentation; nnUNetManager for managing segmentation models and workflows.
Finite element modelling parosol-py for image-based micro finite element analysis in Python.
Image I/O tools aimio-py for reading Scanco AIM, ISQ, SCV, GOBJ, RAD, and RSQ files, and writing AIM files.

Research and collaboration

Visit the lab website for my background, publications, student opportunities, and lab information. For software questions and contributions, open an issue in the relevant lab repository.

Personal repository languages

Auto-updated from public repositories.

Language Share Repositories
JavaScript 55.0% 1
HTML 40.7% 1
Python 4.3% 1

This overview covers repositories in my personal account. The lab software is hosted in the organization linked above.

Pinned Loading

  1. walle-lab/BoneQuantMRI walle-lab/BoneQuantMRI Public

    MATLAB tool for analyzing MRI bone images using ROI-based segmentation and phantom calibration.

    MATLAB 1

  2. walle-lab/nnUNetManager walle-lab/nnUNetManager Public

    nnUNetManager is a command-line tool designed to manage and execute nnUNet models for medical image segmentation tasks.

    Python 2

  3. Bonelab/spineFE-benchmark Bonelab/spineFE-benchmark Public

    Code and instructions to reproduce the analyses from our study comparing linear and nonlinear finite element models of vertebral strength across the thoracic and lumbar spine using the VERSE19 data…

    Jupyter Notebook 3 1

  4. walle-lab/MotionScoreCNN walle-lab/MotionScoreCNN Public archive

    Code for Motion Grading of HR-pQCT scans

    Python