GSE142512

GSE142512 is a Bioconductor ExperimentHub data package for processed DNA methylation resources derived from GEO Series GSE142512.

The package provides access to two Zenodo-hosted RangedSummarizedExperiment resources:

GSE142512_GPL13534_450K: Illumina HumanMethylation450 data with 485,512 CpG loci and 184 samples.
GSE142512_GPL21145_EPIC: Infinium MethylationEPIC data with 865,859 CpG loci and 211 samples.

Both resources include beta, M, and CN assays, hg19 genomic ranges, and sample-level phenotype metadata.

The hosted files are available from Zenodo:

The source GEO record is:

Installation

Install GSE142512 from Bioconductor with:

if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("GSE142512")

The resources can be queried with:

library(ExperimentHub)
hub <- ExperimentHub()
query(hub, "GSE142512")

or loaded through the package helpers:

library(GSE142512)
se450k <- GSE142512(platform = "450K")
seEPIC <- GSE142512(platform = "EPIC")

The same resources can also be loaded with their resource-title accessors:

se450k <- GSE142512_GPL13534_450K()
seEPIC <- GSE142512_GPL21145_EPIC()