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crohns-disease

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A multivariable MbWAS pipeline identifying taxonomic biomarkers of gut dysbiosis in Crohn's Disease. Implements zero-replaced Centered Log-Ratio (CLR) transformations and two-part hurdle regression models integrated via the Cauchy combination test to contrast the HMP2 / IBDMDB cohort.

  • Updated Jun 11, 2026
  • Python

A computational metataxonomics pipeline for 16S rRNA-seq, quantifying mucosal dysbiosis, differential microbial abundance, and co-occurrence network topologies to identify keystone taxa in Crohn's Disease.

  • Updated May 9, 2026
  • R

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